"It’s a big business, it's a trillion-dollar global industry, it's a really attractive industry, it's always been competitive," Khosrowshahi said. "So, we welcome Amazon to the party, so to speak. It;s a business that has been growing really really well, so it's no wonder that other companies are looking at." When asked about whether Expedia can put a barrier on Amazon’s entry, Khosrowshahi said, "I don’t think that there is any absolute lock-up factor because this is a too big a business, but we do have over 300,000 hotels now in our system on a global basis. It's going to take a lot of catching up to do for any player out there to get to the size and scale that we have on a global basis. So, we're really confident of our prospects going forward." Watch the video on CNBC